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DOAJ Open Access 2023

Novel Triple Stimuli Responsive Interpenetrating Poly(Carboxybetaine Methacrylate)/Poly(Sulfobetaine Methacrylate) Network

Konstans Ruseva Katerina Todorova Tanya Zhivkova Rositsa Milcheva Dimitar Ivanov +3 lainnya
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Abstrak

The study reports the synthesis and characterization of novel triple stimuli responsive interpenetrating polymer network (IPN) based on two polyzwitterionic networks, namely of poly(carboxybetaine methacrylate) and poly(sulfobetaine methacrylate). The zwitterionic IPN hydrogel demonstrates the ability to expand or shrink in response to changes in three “biological” external stimuli such as temperature, pH, and salt concentration. The IPN hydrogel shows good mechanical stability. In addition, other important features such as non-cytotoxicity and antibiofouling activity against three widespread bacteria as <i>P. Aeruginosa</i>, <i>A. Baumanii,</i> and <i>K. Pneumoniae</i> are demonstrated. The in vivo behavior of the novel zwitterionic IPN hydrogel suggests that this smart material has very good potential as a biomaterial.

Topik & Kata Kunci

Science Chemistry Inorganic chemistry General. Including alchemy

Penulis (8)

K

Konstans Ruseva

K

Katerina Todorova

T

Tanya Zhivkova

R

Rositsa Milcheva

D

Dimitar Ivanov

P

Petar Dimitrov

R

Radostina Alexandrova

E

Elena Vassileva

Format Sitasi

APA MLA BibTeX
Ruseva, K., Todorova, K., Zhivkova, T., Milcheva, R., Ivanov, D., Dimitrov, P. et al. (2023). Novel Triple Stimuli Responsive Interpenetrating Poly(Carboxybetaine Methacrylate)/Poly(Sulfobetaine Methacrylate) Network. https://doi.org/10.3390/gels9020090

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Informasi Jurnal
Tahun Terbit
2023
Sumber Database
DOAJ
DOI
10.3390/gels9020090
Akses
Open Access ✓