DOAJ Open Access 2021

Swelling and Drug Release in Polymers through the Theory of Poisson–Kac Stochastic Processes

Alessandra Adrover Claudia Venditti Massimiliano Giona

Abstrak

Experiments on swelling and solute transport in polymeric systems clearly indicate that the classical parabolic models fail to predict typical non-Fickian features of sorption kinetics. The formulation of moving-boundary transport models for solvent penetration and drug release in swelling polymeric systems is addressed hereby employing the theory of Poisson–Kac stochastic processes possessing finite propagation velocity. The hyperbolic continuous equations deriving from Poisson–Kac processes are extended to include the description of the temporal evolution of both the Glass–Gel and the Gel–Solvent interfaces. The influence of polymer relaxation time on sorption curves and drug release kinetics is addressed in detail.

Topik & Kata Kunci

Science Chemistry Inorganic chemistry General. Including alchemy

Penulis (3)

Alessandra Adrover

Claudia Venditti

Massimiliano Giona

Format Sitasi

APA MLA BibTeX

Adrover, A., Venditti, C., Giona, M. (2021). Swelling and Drug Release in Polymers through the Theory of Poisson–Kac Stochastic Processes. https://doi.org/10.3390/gels7010032

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.3390/gels7010032

Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.3390/gels7010032
Akses: Open Access ✓