DOAJ Open Access 2021

Numerical Study of Bloodstream Diffusion of the New Generation of Drug-Eluting Stents in Coronary Arteries

Leandro Marques Gustavo R. Anjos

Abstrak

The present work aims at developing a numerical study on the drug diffusion in the bloodstream in a coronary artery with drug-eluting stent implanted. The blood was modeled as a single-phase, incompressible and Newtonian fluid and the Navier–Stokes equation was approximated according to the Finite Element Method (FEM). The dynamics of drug-eluting concentration in bloodstream was investigated using four drug-eluting stents with different mass diffusivities in microchannels with variable cross sections, including a real coronary artery geometry with atherosclerosis. The results reveal complex drug concentration patterns and accumulation in the vicinity of the fat buildup.

Topik & Kata Kunci

Thermodynamics Descriptive and experimental mechanics

Penulis (2)

Leandro Marques

Gustavo R. Anjos

Format Sitasi

APA MLA BibTeX

Marques, L., Anjos, G.R. (2021). Numerical Study of Bloodstream Diffusion of the New Generation of Drug-Eluting Stents in Coronary Arteries. https://doi.org/10.3390/fluids6020071

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Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.3390/fluids6020071
Akses: Open Access ✓