Microbial Manufacturing of Recombinant Protein: Recent Advances, Challenges, and Strategies
Abstrak
Proteins are fundamental to life and indispensable for human physiological activities. However, traditional proteins derived from natural sources such as animals and plants face challenges including low extraction efficiency and limited availability. Therefore, recombinant proteins produced via microbial manufacturing have emerged as a promising alternative. This review specifically focuses on the production of recombinant protein with certain specific functional characteristics, using microorganisms. Owing to their unique functional attributes, such proteins are in increasing demand in diverse fields, including food, medicine, and agriculture. Firstly, this review outlines the definition of recombinant protein and summarizes the microbial manufacturing and applications of nine typical proteins with certain specific functional characteristics. Secondly, the strategies of utilizing microorganisms for the efficient production and purification of recombinant proteins was systematically reviewed.
Topik & Kata Kunci
Penulis (9)
Yonghan Chen
Zhiyan Zhang
Chuan Wang
Qingjing Huang
Lixiu Yan
Chang Sun
Jun Kang
Jiamin Zhang
Jie Cheng
Akses Cepat
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Cek di sumber asli →- Tahun Terbit
- 2026
- Sumber Database
- DOAJ
- DOI
- 10.3390/fermentation12030132
- Akses
- Open Access ✓