DOAJ Open Access 2025

Design and Operation of a Multifunctional Pilot-Scale Bioreactor for Enhanced Aerobic Fermentation

Mauro Moresi

Abstrak

The primary aim of this work was to share the results from a Research Project supported by the Italian National Research Council, which led to the development of a versatile jacketed tower bioreactor. Designed to optimize oxygen transfer efficiency and process control, the reactor incorporated a reciprocating air compressor, centrifugal pumps, a draft tube with or without perforated plates, and a series of gas–liquid ejectors. Its flexible design enabled operation in both airlift and ejector-loop modes, making it suitable for a wide range of aerobic fermentation processes. By sharing the detailed engineering design, operational procedures of this pilot-scale bioreactor, as well as its performance data when cultivating yeasts on whey and potato wastewater, a detailed blueprint was given to researchers seeking to advance bioreactor technology, particularly in the context of emerging fields like cultured meat production, pharmaceutical manufacturing, and environmental bioremediation.

Penulis (1)

M

Mauro Moresi

Format Sitasi

Moresi, M. (2025). Design and Operation of a Multifunctional Pilot-Scale Bioreactor for Enhanced Aerobic Fermentation. https://doi.org/10.3390/fermentation11020101

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Informasi Jurnal
Tahun Terbit
2025
Sumber Database
DOAJ
DOI
10.3390/fermentation11020101
Akses
Open Access ✓