Innovative Drug Delivery Systems: The Comprehensive Role of Natural Polymers in Fast-Dissolving Tablets

Fast-dissolving tablets (FDTs) have arisen as a novel way to tackle issues encountered by patients with dysphagia, including youngsters, older people, and those with neurodegenerative or developmental disabilities. This review emphasises the crucial function of natural polymers as super disintegrants in improving fast-disintegrating tablet formulation. Natural polymers, such as chitosan, guar gum, xanthan gum, and fenugreek seed mucilage, are biocompatible, biodegradable, and offer better affordability than synthetics. Natural polymers can quickly break down and disintegrate oral tablets. They also help accelerate drug release bioavailability and patient compliance. This article discusses the benefits of natural polymers, such as environmentally sustainable processing, cost effectiveness, and patient engagement, as well as challenges and limitations. The comprehensive comparison between natural polymers and synthetic polymers emphasises the benefits of natural substances to overcome challenges in the production and promotion of sustainable pharmaceutical practices. Spray drying, freezing, and nanotechnology are advancements in FDT production technology. Apart from its ownership, like Zydis and Durasolv, the combination of these techniques aids in the creation of a medicine system that may be adjusted. They prioritize patients and are also effective. Prospective studies should focus on the expansion of natural polymer procurement and distillation processes to improve the use of FDT.