Sustainable Pharmaceutical Development Utilizing <i>Vigna mungo</i> Polymer Microbeads
Abstrak
This study explores the potential of <i>Vigna mungo</i> gum as a sustainable and innovative natural polymer for developing microbeads for the controlled delivery of vildagliptin, a widely used antidiabetic agent. Unlike conventional natural polymers, <i>Vigna mungo</i> gum offers unique biocompatibility, biodegradability, and an eco-friendly production process, distinguishing it as a superior candidate for drug delivery systems. Microbeads were prepared by combining <i>Vigna mungo</i> gum with sodium alginate and inducing gelation using calcium carbonate. Scanning electron microscopy (SEM) revealed a rough, porous microbead surface, advantageous for drug encapsulation and controlled release. Drug release studies demonstrated sustained release kinetics, highlighting the effectiveness of this formulation. These findings underscore the novelty of <i>Vigna mungo</i> gum as a promising platform for antidiabetic drug delivery, providing a sustainable alternative to existing polymer systems.
Topik & Kata Kunci
Penulis (2)
Krishnaveni Manubolu
Raveesha Peeriga
Akses Cepat
- Tahun Terbit
- 2025
- Sumber Database
- DOAJ
- DOI
- 10.3390/engproc2024081014
- Akses
- Open Access ✓