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DOAJ Open Access 2021

Next-Generation Sequencing Analysis of Root Canal Microbiota Associated with a Severe Endodontic-Periodontal Lesion

Alessio Buonavoglia Gianvito Lanave Michele Camero Marialaura Corrente Antonio Parisi +2 lainnya
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Abstrak

A patient with an unusual endo-periodontal lesion, without coronal decay or damage, likely caused by a deep periodontal lesion with subsequent endodontic bacterial migration, required medical care. Next-generation sequencing (NGS) was used to assess the endodontic microbiota in vestibular and palatal canals after tooth extraction, evidencing a predominant population (Fusobacterium nucleatum) in one endodontic canal, and a mixed bacterial population with six major populations almost equally distributed in the other endodontic canal (<i>F. nucleatum, Porphyromonas gingivalis</i>, <i>P. endodontis, Parvimonas, Peptostreptococcus stomatis, Prevotella multiformis</i>). These data could suggest different, separated ecologic niches in the same endodontic system, with potentially different pathogenicity levels, clinical manifestations and prognoses for every single canal of the same tooth.

Topik & Kata Kunci

Medicine (General)

Penulis (7)

A

Alessio Buonavoglia

G

Gianvito Lanave

M

Michele Camero

M

Marialaura Corrente

A

Antonio Parisi

V

Vito Martella

C

Carlo Prati

Format Sitasi

APA MLA BibTeX
Buonavoglia, A., Lanave, G., Camero, M., Corrente, M., Parisi, A., Martella, V. et al. (2021). Next-Generation Sequencing Analysis of Root Canal Microbiota Associated with a Severe Endodontic-Periodontal Lesion. https://doi.org/10.3390/diagnostics11081461

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Informasi Jurnal
Tahun Terbit
2021
Sumber Database
DOAJ
DOI
10.3390/diagnostics11081461
Akses
Open Access ✓