DOAJ Open Access 2023

Pediatric Posterior Fossa ATRT: A Case Report, New Treatment Strategies and Perspectives

Luca Paun Alexandre Lavé Gianpaolo Jannelli Kristof Egervari Insa Janssen +3 lainnya

Abstrak

Posterior fossa atypical teratoid rhabdoid tumor (ATRT) is a rare childhood tumor usually associated with a dismal prognosis. Although upfront surgical gross total resection (GTR) has classically been the first line of treatment, new multimodal treatments, including two-stage surgery, are showing promising results in terms of overall survival (OS) and complication rate. We present a case of a 9-month-old child treated with two-staged surgery and chemotherapy. When deemed risky, multimodal treatments, including staged surgeries, can be a safe alternative to reduce surgical mortality and morbidity. At 23 months old, the patient had normal global development and no major impact on quality of life. We, therefore, discuss the most recent advancements from a treatment perspective, including molecular targeting.

Topik & Kata Kunci

Neurosciences. Biological psychiatry. Neuropsychiatry

Penulis (8)

Luca Paun

Alexandre Lavé

Gianpaolo Jannelli

Kristof Egervari

Insa Janssen

Karl Schaller

André O. von Bueren

Andrea Bartoli

Format Sitasi

APA MLA BibTeX

Paun, L., Lavé, A., Jannelli, G., Egervari, K., Janssen, I., Schaller, K. et al. (2023). Pediatric Posterior Fossa ATRT: A Case Report, New Treatment Strategies and Perspectives. https://doi.org/10.3390/brainsci13050712

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.3390/brainsci13050712

Informasi Jurnal

Tahun Terbit: 2023
Sumber Database: DOAJ
DOI: 10.3390/brainsci13050712
Akses: Open Access ✓