The mediating role of psychological inflexibility and social avoidance in relationship between body image disturbance and depression among young adults with acne in China

BackgroundAcne impairs physical appearance and triggers significant psychological distress, particularly depression, in young adults, but the underlying psychological mechanisms remain underexplored.ObjectivesThis study aimed to examine the potential mediating associations of psychological inflexibility and social avoidance in the relationship between body image disturbance and depressive tendencies among young adults with acne in East China, based on the Acceptance and Commitment Therapy (ACT) framework.MethodsA cross-sectional survey was conducted among 201 young adults (18–29 years, 72.1% female) with acne from two tertiary hospitals in East China between December 2024 and February 2025. Validated instruments were used to assess body image disturbance (BIDQ), psychological inflexibility (AAQ-II), social avoidance (SADS-SA), and depression (PHQ-9). A serial mediation model (PROCESS Model 6) was analyzed via SPSS 29 with 5,000 bootstrap samples.ResultsCorrelation analysis showed significant positive relationships between body image disturbance, psychological inflexibility, social avoidance, and depression (all p < 0.01). Mediation analysis revealed that body image disturbance had a significant total effect on depression [Effect = 0.147, 95% CI (0.088, 0.205)], while its direct effect was non-significant. Two indirect pathways accounted for 84.1% of the total effect: (1) a single mediation through psychological inflexibility (70.8% of the effect); and (2) a serial mediation through psychological inflexibility and social avoidance (7.4% of the effect). Additionally, acne severity significantly predicted psychological inflexibility (β = 0.184, p = 0.012).ConclusionBody image disturbance indirectly influences depression primarily through the pathways of psychological inflexibility and social avoidance. Integrating ACT into dermatological care to enhance psychological flexibility may effectively alleviate depressive symptoms in acne patients.