DOAJ Open Access 2022

High Carbohydrate Antigen 19-9 Levels Indicate Poor Prognosis of Upper Tract Urothelial Carcinoma

Seung-hwan Jeong Jang Hee Han Chang Wook Jeong Chang Wook Jeong Hyeon Hoe Kim +7 lainnya

Abstrak

Upper tract urothelial carcinoma (UTUC) occurs in urothelial cells from the kidney and the ureters. Carbohydrate antigen 19-9 (CA 19-9) is a tumor marker for pancreatic and gastrointestinal cancers, and its high levels are associated with poor prognosis in bladder cancer. In this study, prospective patients enrolled in the registry of Seoul National University were retrospectively examined to determine the clinical significance of CA 19-9 in UTUC. In 227 patients, high serum CA 19-9 levels reflected a high tumor burden represented by high T and N stages, leading to adverse prognosis in metastasis-free or overall survival. Subsequently, propensity score matching analysis showed that the CA 19-9 level is an independent prognostic factor of UTUC.

Topik & Kata Kunci

Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Penulis (12)

Seung-hwan Jeong

Jang Hee Han

Chang Wook Jeong

Hyeon Hoe Kim

Cheol Kwak

Hyeong Dong Yuk

Ja Hyeon Ku

Format Sitasi

APA MLA BibTeX

Jeong, S., Han, J.H., Jeong, C.W., Jeong, C.W., Kim, H.H., Kim, H.H. et al. (2022). High Carbohydrate Antigen 19-9 Levels Indicate Poor Prognosis of Upper Tract Urothelial Carcinoma. https://doi.org/10.3389/fonc.2022.858813

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.3389/fonc.2022.858813

Informasi Jurnal

Tahun Terbit: 2022
Sumber Database: DOAJ
DOI: 10.3389/fonc.2022.858813
Akses: Open Access ✓