DOAJ Open Access 2021

Organoids for the Study of Retinal Development and Developmental Abnormalities

Anne Vielle Anne Vielle Yuna K. Park Conner Secora Conner Secora +3 lainnya

Abstrak

The cumulative knowledge of retina development has been instrumental in the generation of retinal organoid systems from pluripotent stem cells; and these three-dimensional organoid models, in turn, have provided unprecedented opportunities for retinal research and translational applications, including the ability to model disease in a human setting and to apply these models to the development and validation of therapeutic drugs. In this review article, we examine how retinal organoids can also contribute to our understanding of retinal developmental mechanisms, how this knowledge can be applied to modeling developmental abnormalities, and highlight some of the avenues that remain to be explored.

Topik & Kata Kunci

Neurosciences. Biological psychiatry. Neuropsychiatry

Penulis (8)

Anne Vielle

Yuna K. Park

Conner Secora

M. Natalia Vergara

Format Sitasi

APA MLA BibTeX

Vielle, A., Vielle, A., Park, Y.K., Secora, C., Secora, C., Secora, C. et al. (2021). Organoids for the Study of Retinal Development and Developmental Abnormalities. https://doi.org/10.3389/fncel.2021.667880

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Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.3389/fncel.2021.667880
Akses: Open Access ✓