DOAJ Open Access 2022

Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study

Denise Battaglini Denise Battaglini Lavienraj Premraj Lavienraj Premraj Matthew Griffee +41 lainnya

Abstrak

IntroductionNeurological manifestations and complications in coronavirus disease-2019 (COVID-19) patients are frequent. Prior studies suggested a possible association between neurological complications and fatal outcome, as well as the existence of potential modifiable risk factors associated to their occurrence. Therefore, more information is needed regarding the incidence and type of neurological complications, risk factors, and associated outcomes in COVID-19.MethodsThis is a pre-planned secondary analysis of the international multicenter observational study of the COVID-19 Critical Care Consortium (which collected data both retrospectively and prospectively from the beginning of COVID-19 pandemic) with the aim to describe neurological complications in critically ill COVID-19 patients and to assess the associated risk factors, and outcomes. Adult patients with confirmed COVID-19, admitted to Intensive Care Unit (ICU) will be considered for this analysis. Data collected in the COVID-19 Critical Care Consortium study includes patients' pre-admission characteristics, comorbidities, severity status, and type and severity of neurological complications. In-hospital mortality and neurological outcome were collected at discharge from ICU, and at 28-days.Ethics and DisseminationThe COVID-19 Critical Care Consortium main study and its amendments have been approved by the Regional Ethics Committee of participating sites. No further approval is required for this secondary analysis.Trial Registration NumberACTRN12620000421932.

Topik & Kata Kunci

Medicine (General)

Penulis (46)

Denise Battaglini

Lavienraj Premraj

Matthew Griffee

Samuel Huth

Jonathon Fanning

Glenn Whitman

Diego Bastos Porto

Rakesh Arora

Lucian Durham

Eric Gnall

Marcelo Amato

Virginie Williams

Alexandre Noel

Sabrina Araujo De Franca

Gordan Samoukovic

Bambang Pujo

David Kent

Eva Marwali

Abdulrahman Al-Fares

Stephanie-Susanne Stecher

Mauro Panigada

Marco Giani

Giuseppe Foti

Paolo Pelosi

Antonio Pesenti

Nicole Marie White

Gianluigi Li Bassi

Jacky Suen

John F. Fraser

Chiara Robba

Sung-Min Cho

Format Sitasi

APA MLA BibTeX

Battaglini, D., Battaglini, D., Premraj, L., Premraj, L., Griffee, M., Huth, S. et al. (2022). Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study. https://doi.org/10.3389/fmed.2022.930217

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Informasi Jurnal

Tahun Terbit: 2022
Sumber Database: DOAJ
DOI: 10.3389/fmed.2022.930217
Akses: Open Access ✓