DOAJ Open Access 2024

Pyroptosis: a new insight into intestinal inflammation and cancer

Limin Chao Wenjing Zhang Yuchao Feng Pei Gao Jinyou Ma

Abstrak

Pyroptosis is an innate immune response triggered by the activation of inflammasomes by various influencing factors, characterized by cell destruction. It impacts the immune system and cancer immunotherapy. In recent years, the roles of pyroptosis and inflammasomes in intestinal inflammation and cancer have been continuously confirmed. This article reviews the latest progress in pyroptosis mechanisms, new discoveries of inflammasomes, mutual regulation between inflammasomes, and their applications in intestinal diseases. Additionally, potential synergistic treatment mechanisms of intestinal diseases with pyroptosis are summarized, and challenges and future directions are discussed, providing new ideas for pyroptosis therapy.

Topik & Kata Kunci

Immunologic diseases. Allergy

Penulis (5)

Limin Chao

Wenjing Zhang

Yuchao Feng

Pei Gao

Jinyou Ma

Format Sitasi

APA MLA BibTeX

Chao, L., Zhang, W., Feng, Y., Gao, P., Ma, J. (2024). Pyroptosis: a new insight into intestinal inflammation and cancer. https://doi.org/10.3389/fimmu.2024.1364911

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Informasi Jurnal

Tahun Terbit: 2024
Sumber Database: DOAJ
DOI: 10.3389/fimmu.2024.1364911
Akses: Open Access ✓