DOAJ Open Access 2024

Diagnostic accuracy of a non-invasive spot-check hemoglobin meter, Masimo Rad-67® pulse CO-Oximeter®, in detection of anemia in antenatal care settings in Kenya

Angela Koech Angela Koech Angela Koech Isaac Mwaniki Joseph Mutunga +111 lainnya

Abstrak

BackgroundPoint of care hemoglobin meters play key roles in increasing access to anemia screening in antenatal care especially in settings with limited access to laboratories. We aimed to determine the diagnostic accuracy of a non-invasive spot-check hemoglobin (SpHb) meter, Masimo Rad-67® Pulse CO-Oximeter®, in the diagnosis of anemia in pregnant women attending antenatal care clinics in Kilifi, Kenya.MethodsThis was a diagnostic accuracy study that retrospectively evaluated SpHb against a validated reference standard of laboratory assessed hemoglobin (Lab Hb) by a SYSMEX XN-330 automated hematology analyzer. The study was nested within a prospective pregnancy cohort study that recruited unselected pregnant women from antenatal care clinics in two public hospitals in Kilifi County, coastal Kenya. Records with both SpHb and Lab Hb were selected from pregnancy visits between May 2021 and December 2022. Linear regression and Bland-Altman analysis were performed to compare the two tests and diagnostic accuracy parameters obtained for the diagnosis of anemia.ResultsA total of 2,975 records (from 2,203 unique participants), with paired SpHb and Lab Hb were analyzed. Linear regression showed a significant but weak positive correlation, a proportional bias of 0.44 (95% CI 0.41–0.47) and a constant of 7.59 (95% CI 7.30–7.87, p < 0.001). The median bias was 1.70 g/dl, with limits of agreement of −0.80 to 4.20. SpHb tended to be higher than Lab Hb on the low hemoglobin range but lower than Lab Hb on the high hemoglobin range. The sensitivity of SpHb in detecting anemia was 18.66%. Prevalence, specificity, positive predictive value, and negative predictive values were 46.37%, 96.77%, 83.33%, and 57.92% respectively.ConclusionOverall, SpHb by Masimo Rad-67® Pulse CO-Oximeter® did not accurately identify pregnant women with anemia and many cases would be missed. We would not recommend its use in antenatal care settings.

Topik & Kata Kunci

Gynecology and obstetrics Women. Feminism

Penulis (116)

Angela Koech

Isaac Mwaniki

Joseph Mutunga

Moses Mukhanya

Emily Mwadime

Marvine Ochieng

Grace Mwashigadi

Hiten D. Mistry

Rachel Craik

Peter von Dadelszen

Marleen Temmerman

Stanley Luchters

Geoffrey Omuse

The PRECISE Network

Patricia Okiro

Onesmus Wanje

Consolata Juma

Charlotte Ndana

Douglas Nyankira

Tindi Otieno

Rose Chebet

Winfred Muithi

Washingtone Owino

Quinter Okello

Michael Ochieng

Margaret Wachira

Kelvin Mbote

Mercy Osele

John Kibwanga

Happy Mdigo

Claire Ngure

Joy Wanja

Claire Kiti

Winnie Nzoka

Grace Anyange

Robin Okello

David Mwadziwe

Ruth Mambo

Sarah Maitha

Juma Gumbo

Jamal Salim

Mary Kalido

Salim Mwakanyenze

Anne Mutua

Asha Tunje

Noveline Khatievi

Nathan Barreh

Belinder Orero

Mwanajuma Khamisi

Eric Mataza

Said Lele

Olivia Kasuu

Susan Sidi

Hassan Kopa

Faith Pola

Umberto D’Alessandro

Anna Roca

Hawanatu Jah

Andrew Prentice

Melisa Martinez-Alvarez

Brahima Diallo

Abdul Sesay

Sambou Suso

Yahaya Idris

Baboucarr Njie

Fatima Touray

Fatoumata Kongira

Modou F.S. Ndure

Gibril Gabbidon

Lawrence Gibba

Abdoulie Bah

Yorro Bah

Esperança Sevene

Anifa Vala

Sonia Maculuve

Corssino Tchavana

Helena Boene

Lazaro Quimice

Salesio Macuacua

Carla Carrilho

Laura A. Magee

Marie-Laure Volvert

Thomas Mendy

Donna Russell

Prestige Tatenda Makanga

Liberty Makacha

Reason Mlambo

Lucilla Poston

Rachel Tribe

Sophie Moore

Tatiana Salisbury

Aris Papageorghiou

Alison Noble

Hannah Blencowe

Veronique Filippi

Joy Lawn

Matt Silver

Joseph Akuze

Ursula Gazeley

Judith Cartwright

Guy Whitley

Sanjeev Krishna

Marianne Vidler

Jing (Larry) Li

Jeff Bone

Mai-Lei (Maggie) Woo Kinshella

Domena Tu

Ash Sandhu

Kelly Pickerill

Carla Carillho

Benjamin Barratt

Format Sitasi

APA MLA BibTeX

Koech, A., Koech, A., Koech, A., Mwaniki, I., Mutunga, J., Mukhanya, M. et al. (2024). Diagnostic accuracy of a non-invasive spot-check hemoglobin meter, Masimo Rad-67® pulse CO-Oximeter®, in detection of anemia in antenatal care settings in Kenya. https://doi.org/10.3389/fgwh.2024.1427261

@article{koech2024, author = {Angela Koech and Angela Koech and Angela Koech and Isaac Mwaniki and Joseph Mutunga and Moses Mukhanya and Emily Mwadime and Marvine Ochieng and Grace Mwashigadi and Hiten D. Mistry and Rachel Craik and Peter von Dadelszen and Marleen Temmerman and Marleen Temmerman and Stanley Luchters and Stanley Luchters and Stanley Luchters and Geoffrey Omuse and The PRECISE Network and Patricia Okiro and Onesmus Wanje and Consolata Juma and Charlotte Ndana and Douglas Nyankira and Tindi Otieno and Rose Chebet and Winfred Muithi and Washingtone Owino and Quinter Okello and Michael Ochieng and Margaret Wachira and Kelvin Mbote and Mercy Osele and John Kibwanga and Happy Mdigo and Claire Ngure and Joy Wanja and Claire Kiti and Winnie Nzoka and Grace Anyange and Robin Okello and David Mwadziwe and Ruth Mambo and Sarah Maitha and Juma Gumbo and Jamal Salim and Mary Kalido and Salim Mwakanyenze and Anne Mutua and Asha Tunje and Noveline Khatievi and Nathan Barreh and Belinder Orero and Mwanajuma Khamisi and Eric Mataza and Said Lele and Olivia Kasuu and Susan Sidi and Hassan Kopa and Faith Pola and Umberto D’Alessandro and Anna Roca and Hawanatu Jah and Andrew Prentice and Melisa Martinez-Alvarez and Brahima Diallo and Abdul Sesay and Sambou Suso and Yahaya Idris and Baboucarr Njie and Fatima Touray and Fatoumata Kongira and Modou F.S. Ndure and Gibril Gabbidon and Lawrence Gibba and Abdoulie Bah and Yorro Bah and Esperança Sevene and Anifa Vala and Sonia Maculuve and Corssino Tchavana and Helena Boene and Lazaro Quimice and Salesio Macuacua and Carla Carrilho and Laura A. Magee and Marie-Laure Volvert and Thomas Mendy and Donna Russell and Prestige Tatenda Makanga and Liberty Makacha and Reason Mlambo and Lucilla Poston and Rachel Tribe and Sophie Moore and Tatiana Salisbury and Aris Papageorghiou and Alison Noble and Hannah Blencowe and Veronique Filippi and Joy Lawn and Matt Silver and Joseph Akuze and Ursula Gazeley and Judith Cartwright and Guy Whitley and Sanjeev Krishna and Marianne Vidler and Jing (Larry) Li and Jeff Bone and Mai-Lei (Maggie) Woo Kinshella and Domena Tu and Ash Sandhu and Kelly Pickerill and Carla Carillho and Benjamin Barratt}, title = {Diagnostic accuracy of a non-invasive spot-check hemoglobin meter, Masimo Rad-67® pulse CO-Oximeter®, in detection of anemia in antenatal care settings in Kenya}, year = {2024}, journal = {DOAJ}, doi = {10.3389/fgwh.2024.1427261}, url = {https://www.frontiersin.org/articles/10.3389/fgwh.2024.1427261/full}, }

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Informasi Jurnal

Tahun Terbit: 2024
Sumber Database: DOAJ
DOI: 10.3389/fgwh.2024.1427261
Akses: Open Access ✓