DOAJ Open Access 2025

Case Report: Extreme resistance to subcutaneous insulin in a cirrhotic patient with new-onset diabetes that resolved after transplantation

Kim Tunez Sara Ringwald-de Meyer Mohammed Barigou Christophe Kosinski

Abstrak

Although an increase in insulin resistance is frequently associated with liver cirrhosis, a condition sometimes referred to as hepatogenic diabetes (HD), the pathophysiology is still poorly understood. Moreover, the management of patients with HD, both diagnostically and therapeutically, is complex. In this article, we present the case of a cirrhotic patient, initially not known to have diabetes or prediabetes, who developed fulminant diabetes overnight, with massive resistance to subcutaneous insulin treatment. Management during hospitalization was extremely complicated, leading to significant staggering of the insulin doses until the liver transplant, which allowed complete normalization of the glycemic profile.

Topik & Kata Kunci

Diseases of the endocrine glands. Clinical endocrinology

Penulis (4)

Kim Tunez

Sara Ringwald-de Meyer

Mohammed Barigou

Christophe Kosinski

Format Sitasi

APA MLA BibTeX

Tunez, K., Meyer, S.R., Barigou, M., Kosinski, C. (2025). Case Report: Extreme resistance to subcutaneous insulin in a cirrhotic patient with new-onset diabetes that resolved after transplantation. https://doi.org/10.3389/fendo.2025.1464532

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.3389/fendo.2025.1464532
Akses: Open Access ✓