DOAJ Open Access 2025

“One-stop” combined percutaneous left atrial appendage and atrial septal defect closure in atrial fibrillation: safety and feasibility from a single-center cohort

Gaofeng Wang Qiqiang Jie Kailing Xu Jie Luo Jing Dong +2 lainnya

Abstrak

BackgroundPatients with atrial fibrillation (AF) and atrial septal defect (ASD) face elevated thromboembolic risks, yet evidence on combined left atrial appendage closure (LAAC) and ASD closure remains limited. We aimed to assess the feasibility and safety of a “one-stop” strategy for simultaneous LAAC and ASD closure.MethodsA retrospective analysis included 40 patients with non-valvular AF and ASD undergoing combined procedures (2016–2024). Procedural success, complications, and long-term outcomes (mean follow-up: 1,194.3 days) were analyzed.ResultsAll procedures were technically successful. No major complications (stroke, device embolization, or death) occurred during follow-up. Peri-device leak (PDL) was observed in 19 patients (47.5%), with only one case of device-related thrombus (resolved with anticoagulation).ConclusionThe “one-stop” approach is a safe and effective strategy for stroke prevention in AF patients with ASD, particularly those unsuitable for long-term anticoagulation.

Topik & Kata Kunci

Diseases of the circulatory (Cardiovascular) system

Penulis (7)

Gaofeng Wang

Qiqiang Jie

Kailing Xu

Jie Luo

Jing Dong

Dujiang Xie

Ling Zhou

Format Sitasi

APA MLA BibTeX

Wang, G., Jie, Q., Xu, K., Luo, J., Dong, J., Xie, D. et al. (2025). “One-stop” combined percutaneous left atrial appendage and atrial septal defect closure in atrial fibrillation: safety and feasibility from a single-center cohort. https://doi.org/10.3389/fcvm.2025.1579786

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.3389/fcvm.2025.1579786
Akses: Open Access ✓