Safety and efficacy of OptiPhos® PLUS (6 phytase) for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding
Abstrak
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of OptiPhos PLUS®, intended to be used as a feed additive for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding. The active substance is 6‐phytase produced by a genetically modified strain of Komagataella phaffii. The EFSA FEEDAP Panel concluded that the genetic modification of the production strain does not give rise to safety concerns. Based on the tolerance studies provided, the Panel concluded that the additive is safe for the target species under the conditions of use with a wide margin of safety. The additive was considered safe also for the consumer and the environment. The additive is not a skin irritant but is a dermal sensitiser. The FEEDAP Panel could not conclude on the eye irritation potential of the additive. Owing to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The FEEDAP Panel concluded that the additive has the potential to be efficacious in increasing the phosphorus utilisation in laying hens at the level of 250 FTU/kg feed. These conclusions were extended to turkeys for breeding and chickens for breeding and extrapolated to minor poultry species for egg production purposes and breeding.
Topik & Kata Kunci
Penulis (32)
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Vasileios Bampidis
Giovanna Azimonti
Maria de Lourdes Bastos
Henrik Christensen
Birgit Dusemund
Mojca Kos Durjava
Maryline Kouba
Marta López‐Alonso
Secundino López Puente
Francesca Marcon
Baltasar Mayo
Alena Pechová
Mariana Petkova
Fernando Ramos
Yolanda Sanz
Roberto Edoardo Villa
Ruud Woutersen
Pier Sandro Cocconcelli
Noël Dierick
Boet Glandorf
Lieve Herman
Miguel Maradona Prieto
Giovanna Martelli
Maria Saarela
Montserrat Anguita
Jaume Galobart
Orsolya Holczknecht
Paola Manini
Elisa Pettenati
Jordi Tarrés‐Call
Fabiola Pizzo
Format Sitasi
Akses Cepat
- Tahun Terbit
- 2020
- Sumber Database
- DOAJ
- DOI
- 10.2903/j.efsa.2020.6161
- Akses
- Open Access ✓