DOAJ Open Access 2020

Safety and efficacy of OptiPhos® PLUS (6 phytase) for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen +27 lainnya

Abstrak

Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of OptiPhos PLUS®, intended to be used as a feed additive for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding. The active substance is 6‐phytase produced by a genetically modified strain of Komagataella phaffii. The EFSA FEEDAP Panel concluded that the genetic modification of the production strain does not give rise to safety concerns. Based on the tolerance studies provided, the Panel concluded that the additive is safe for the target species under the conditions of use with a wide margin of safety. The additive was considered safe also for the consumer and the environment. The additive is not a skin irritant but is a dermal sensitiser. The FEEDAP Panel could not conclude on the eye irritation potential of the additive. Owing to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The FEEDAP Panel concluded that the additive has the potential to be efficacious in increasing the phosphorus utilisation in laying hens at the level of 250 FTU/kg feed. These conclusions were extended to turkeys for breeding and chickens for breeding and extrapolated to minor poultry species for egg production purposes and breeding.

Penulis (32)

E

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

V

Vasileios Bampidis

G

Giovanna Azimonti

M

Maria de Lourdes Bastos

H

Henrik Christensen

B

Birgit Dusemund

M

Mojca Kos Durjava

M

Maryline Kouba

M

Marta López‐Alonso

S

Secundino López Puente

F

Francesca Marcon

B

Baltasar Mayo

A

Alena Pechová

M

Mariana Petkova

F

Fernando Ramos

Y

Yolanda Sanz

R

Roberto Edoardo Villa

R

Ruud Woutersen

P

Pier Sandro Cocconcelli

N

Noël Dierick

B

Boet Glandorf

L

Lieve Herman

M

Miguel Maradona Prieto

G

Giovanna Martelli

M

Maria Saarela

M

Montserrat Anguita

J

Jaume Galobart

O

Orsolya Holczknecht

P

Paola Manini

E

Elisa Pettenati

J

Jordi Tarrés‐Call

F

Fabiola Pizzo

Format Sitasi

(FEEDAP), E.P.o.A.a.P.o.S.u.i.A.F., Bampidis, V., Azimonti, G., Bastos, M.d.L., Christensen, H., Dusemund, B. et al. (2020). Safety and efficacy of OptiPhos® PLUS (6 phytase) for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding. https://doi.org/10.2903/j.efsa.2020.6161

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Informasi Jurnal
Tahun Terbit
2020
Sumber Database
DOAJ
DOI
10.2903/j.efsa.2020.6161
Akses
Open Access ✓