DOAJ Open Access 2023

Fatty acid correlations with HOMA-IR and HOMA-% β are differentially dictated by their serum free and total pools and flaxseed oil supplementation

Barre Douglas E. Mizier-Barre Kazimiera A. Griscti Odette Hafez Kevin

Abstrak

Objective. The intent of the present study was to test two hypotheses. The primary hypothesis was that there would be differences between blood serum individual free fatty acids (SIFFA) and serum individual total fatty acids (SITFA) in terms of their different relationships (correlations) to each of homeostatic model assessment-individual insulin resistance (HOMA-IR) and homeostatic model assessment-individual insulin resistance-percentage β-cell function (HOMA-% β) remaining in human type 2 diabetic patients with pre-flaxseed oil (FXO) and pre-safflower oil (SFO) administration. The secondary hypothesis was that FXO (rich in alpha-linolenic acid, ALA) supplementation would alter these correlations differently in the SIFFA and STIFFA pools in comparison with the placebo SFO (poor in ALA).

Penulis (4)

B

Barre Douglas E.

M

Mizier-Barre Kazimiera A.

G

Griscti Odette

H

Hafez Kevin

Format Sitasi

E., B.D., A., M.K., Odette, G., Kevin, H. (2023). Fatty acid correlations with HOMA-IR and HOMA-% β are differentially dictated by their serum free and total pools and flaxseed oil supplementation. https://doi.org/10.2478/enr-2023-0003

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Informasi Jurnal
Tahun Terbit
2023
Sumber Database
DOAJ
DOI
10.2478/enr-2023-0003
Akses
Open Access ✓