Applying physical science techniques and CERN technology to an unsolved problem in radiation treatment for cancer: the multidisciplinary ‘VoxTox’ research programme
Abstrak
The VoxTox research programme has applied expertise from the physical sciences to the problem of radiotherapy toxicity, bringing together expertise from engineering, mathematics, high energy physics (including the Large Hadron Collider), medical physics and radiation oncology. In our initial cohort of 109 men treated with curative radiotherapy for prostate cancer, daily image guidance computed tomography (CT) scans have been used to calculate delivered dose to the rectum, as distinct from planned dose, using an automated approach. Clinical toxicity data have been collected, allowing us to address the hypothesis that delivered dose provides a better predictor of toxicity than planned dose.
Topik & Kata Kunci
Penulis (35)
Neil Gunn Burnet
Jessica Scaife
Marina Romanchikova
Simon Thomas
Amy Bates
Emma Wong
David Noble
Leila Shelley
Simon Bond
Julia Forman
Andrew Hoole
Gillian Barnett
Frederic Brochu
Michael Simmons
Raj Jena
Karl Harrison
Ping Lin Yeap
Amelia Drew
Emma Silvester
Patrick Elwood
Hannah Pullen
Andrew Sultana
Shannon Seah
Megan Wilson
Simon Russell
Richard Benson
Yvonne Rimmer
Sarah Jefferies
Nicolette Taku
Mark Gurnell
Andrew Powlson
Carola-Bibiane Schönlieb
Xiaohao Cai
Michael Sutcliffe
Michael Parker
Format Sitasi
Akses Cepat
- Tahun Terbit
- 2017
- Sumber Database
- DOAJ
- DOI
- 10.23726/cij.2017.457
- Akses
- Open Access ✓