DOAJ Open Access 2018

Role of genetic factors in the development of diabetic distal symmetric polyneuropathy (review of literature and own researches)

I.А. Zoriy N.V. Pashkovska

Abstrak

The article presents data of the literature review and own observations on studying the role of genetic factors in the risk of development and progression of severe complications of diabetic distal symmetric polyneuropathy. It was found that in patients with non-insulin-dependent (type 2) diabetes mellitus complicated by distal symmetric polyneuropathy, there is an association between the homozygous ТТ genotype of endothelial nitric oxide synthase gene G894T polymorphism and significant subjective symptoms, the presence of axonal lesion of motor nerves according to electroneuromyography, with an increase in the level of glycated hemoglobin, and also in the content of lipid peroxidation products.

Topik & Kata Kunci

Diseases of the endocrine glands. Clinical endocrinology

Penulis (2)

I.А. Zoriy

N.V. Pashkovska

Format Sitasi

APA MLA BibTeX

Zoriy, I., Pashkovska, N. (2018). Role of genetic factors in the development of diabetic distal symmetric polyneuropathy (review of literature and own researches). https://doi.org/10.22141/2224-0721.14.4.2018.140196

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Informasi Jurnal

Tahun Terbit: 2018
Sumber Database: DOAJ
DOI: 10.22141/2224-0721.14.4.2018.140196
Akses: Open Access ✓