DOAJ
Open Access
2019
The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study
Masoud Keikha
mohsen Karbalaei Zadeh Babaki
Luiz Augusto Marcondes Fonseca
Jorge Casseb
Abstrak
Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus, which is the causative agent of adult T-cell leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Evidence suggests that the interaction of HTLV-1 with the cellular-immune system plays a key role in the development of HAM/TSP. However, the main mechanism in this regard remains unknown. The present study aimed to review the HAM/TSP pathogenesis, current status of HTLV-1 in Iran, and available treatments for HTLV-1 infection.
Topik & Kata Kunci
Penulis (4)
M
Masoud Keikha
m
mohsen Karbalaei Zadeh Babaki
L
Luiz Augusto Marcondes Fonseca
J
Jorge Casseb
Akses Cepat
Informasi Jurnal
- Tahun Terbit
- 2019
- Sumber Database
- DOAJ
- DOI
- 10.22038/rcm.2019.38759.1266
- Akses
- Open Access ✓