DOAJ Open Access 2019

The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study

Masoud Keikha mohsen Karbalaei Zadeh Babaki Luiz Augusto Marcondes Fonseca Jorge Casseb

Abstrak

Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus, which is the causative agent of adult T-cell leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Evidence suggests that the interaction of HTLV-1 with the cellular-immune system plays a key role in the development of HAM/TSP. However, the main mechanism in this regard remains unknown. The present study aimed to review the HAM/TSP pathogenesis, current status of HTLV-1 in Iran, and available treatments for HTLV-1 infection.

Topik & Kata Kunci

Penulis (4)

M

Masoud Keikha

m

mohsen Karbalaei Zadeh Babaki

L

Luiz Augusto Marcondes Fonseca

J

Jorge Casseb

Format Sitasi

Keikha, M., Babaki, m.K.Z., Fonseca, L.A.M., Casseb, J. (2019). The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study. https://doi.org/10.22038/rcm.2019.38759.1266

Akses Cepat

Informasi Jurnal
Tahun Terbit
2019
Sumber Database
DOAJ
DOI
10.22038/rcm.2019.38759.1266
Akses
Open Access ✓