DOAJ Open Access 2016

PROBLEM OF GENERIC REPLACEMENT: ADVANTAGES AND DISADVANTAGES

S. N. Tolpygina S. Yu. Martsevich

Abstrak

The main differences between original and generic drugs as well as registration criteria for generics are described. Possible reasons of discrepancy in bioequivalence and therapeutic equivalence of original and generic drugs are reviewed. The examples of such a discrepancy as a result of comparative clinical trails (enalapril maleate) are discussed. Approaches to planning of comparative trails on drug therapeutic equivalence are presented.

Topik & Kata Kunci

Therapeutics. Pharmacology Diseases of the circulatory (Cardiovascular) system

Penulis (2)

S. N. Tolpygina

S. Yu. Martsevich

Format Sitasi

APA MLA BibTeX

Tolpygina, S.N., Martsevich, S.Y. (2016). PROBLEM OF GENERIC REPLACEMENT: ADVANTAGES AND DISADVANTAGES. https://doi.org/10.20996/1819-6446-2009-5-1-63-68

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Informasi Jurnal

Tahun Terbit: 2016
Sumber Database: DOAJ
DOI: 10.20996/1819-6446-2009-5-1-63-68
Akses: Open Access ✓