DOAJ Open Access 2020

Detection of Ofloxacin by Differential Pulse Voltammetry in Drugs Based on a Novel p-Aminobenzene Sulfonic Acid/Graphene Electrochemical Sensor

Xiaojing Si Chen Bai Xia Gong Jingting Han Zichao Chen +1 lainnya

Abstrak

This work demonstrates fabrication and performance (towards ofloxacin (OFL) detection) of a unique electrochemical sensor, composed of p-aminobenzene sulfonic acid (ASBA) and grapheme (GR). For this purpose, a glassy carbon electrode (GCE) was coated by GR using electrochemical deposition and then electro-polymerized by ABSA. The surface and morphology of the resulting composite pABSA/GR/GCE were analyzed using scanning electron microscopy. Oxidation peak currents obtained from the differential pulse voltammograms with the assistance of the composite pASBA/GR/GCE showed linear correlation to the OFL concentrations in the 0.1-40 μmol/L range with the detection limits of acetaminophen is 0.03 μmol/L (S/N = 3). We also demonstrated OFL detection using pASBA/GR/GCE in pharmaceutical formulations. These results indicate that pASBA/GR/GCE has very strong potential as an electro-analytical sensor for the detection of components in pharmaceutical formulations.

Topik & Kata Kunci

Industrial electrochemistry Physical and theoretical chemistry

Penulis (6)

Xiaojing Si

Chen Bai

Xia Gong

Jingting Han

Zichao Chen

Yaping Ding

Format Sitasi

APA MLA BibTeX

Si, X., Bai, C., Gong, X., Han, J., Chen, Z., Ding, Y. (2020). Detection of Ofloxacin by Differential Pulse Voltammetry in Drugs Based on a Novel p-Aminobenzene Sulfonic Acid/Graphene Electrochemical Sensor. https://doi.org/10.20964/2020.07.46

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Informasi Jurnal

Tahun Terbit: 2020
Sumber Database: DOAJ
DOI: 10.20964/2020.07.46
Akses: Open Access ✓