DOAJ Open Access 2016

Detection Aristolochic Acids 1 and 2 in Costustoot via Electrochemical Method and Liquid Chromatography

Junping Zhang Zheng Wei Aihua Zhang Yi Zhao Guochen Zhao +4 lainnya

Abstrak

Aristolochic acids (1 and 2), a component in medicinal plants, have been reported as the cause of end-stage renal failure. For the identification and quantity determination of aristolochic acid a and 2 (AA-1 and AA-2) in Radix Aucklandiae, a liquid chromatography with electrochemical detection system was constructed in this paper. Both of the chromatographic peak heights for AA-1 and AA-2 at the detection potential of -0.8 V were found to be related linearly with the concentrations ranging from 10 ng/mL to 50 μg/mL. The limit of detection (S/N = 3) of AA-1 and AA-2 are 3.7 and 3.4 ng/mL, respectively.

Penulis (9)

J

Junping Zhang

Z

Zheng Wei

A

Aihua Zhang

Y

Yi Zhao

G

Guochen Zhao

X

Xiaoping Cai

W

Weifeng Cui

Y

Yanchun Wang

J

Junming Fan

Format Sitasi

Zhang, J., Wei, Z., Zhang, A., Zhao, Y., Zhao, G., Cai, X. et al. (2016). Detection Aristolochic Acids 1 and 2 in Costustoot via Electrochemical Method and Liquid Chromatography. https://doi.org/10.20964/2016.08.11

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Informasi Jurnal
Tahun Terbit
2016
Sumber Database
DOAJ
DOI
10.20964/2016.08.11
Akses
Open Access ✓