Identification of plasmid IncQ1 and NTEKPC-IId harboring bla KPC-2 in isolates from Klebsiella pneumoniae infections in patients from Recife-PE, Brazil
Abstrak
Abstract INTRODUCTION: This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates. METHODS: Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using polymerase chain reaction and plasmid DNA sequencing. RESULTS: The bla KPC-2 gene was located between ISKpn6 and a resolvase tnpR in the non-Tn4401 element (NTEKPC-IId). It was detected on a plasmid belonging to the IncQ1 group. CONCLUSIONS To our knowledge, this is the first report of the presence of the bla KPC-2 gene in the NTEKPC-IId element carried by plasmid IncQ1 from infections in Brazil.
Topik & Kata Kunci
Penulis (8)
Giselle Jucá de Lima
Alexsandra Maria Lima Scavuzzi
Elizabeth Maria Bispo Beltrão
Elza Ferreira Firmo
Érica Maria de Oliveira
Sibele Ribeiro de Oliveira
Antônio Mauro Rezende
Ana Catarina de Souza Lopes
Format Sitasi
Akses Cepat
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Cek di sumber asli →- Tahun Terbit
- 2020
- Sumber Database
- DOAJ
- DOI
- 10.1590/0037-8682-0526-2019
- Akses
- Open Access ✓