DOAJ Open Access 2025

Does modifying energy metabolism alter cellular signaling and proliferation in KRAS mutant NSCLCs?

Cingir Koker Sahika Dogan Turacli Irem

Abstrak

The capacity to sense and respond to cellular energy stress is an important factor in tumorigenesis. We aimed to investigate the proliferation patterns of KRAS-mutant NSCLC cell lines (A549, Calu-1, H2009) under high (HG) and low glucose (LG) conditions w/wo DCA, which alters metabolic pathways and promotes oxidative phosphorylation.

Topik & Kata Kunci

Biochemistry

Penulis (2)

Cingir Koker Sahika

Dogan Turacli Irem

Format Sitasi

APA MLA BibTeX

Sahika, C.K., Irem, D.T. (2025). Does modifying energy metabolism alter cellular signaling and proliferation in KRAS mutant NSCLCs?. https://doi.org/10.1515/tjb-2025-0030

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.1515/tjb-2025-0030
Akses: Open Access ✓