Research and application effect analysis on infection prevention and control quality improvement in central sterile supply department based on HFMEA and SPO methods

ObjectiveThe present study aims to investigate the application efficacy of the Supply-Process-Output (SPO) and Healthcare Failure Mode and Effects Analysis (HFMEA) methodologies in infection prevention and quality management practices within a central sterile supply department (CSSD).MethodsBased on literature reviews and the specific circumstances in an institution, an integrated systemic prevention framework was constructed by combining HFMEA-based failure mode analysis with the SPO model. A risk assessment scale for infection control in CSSD was developed to identify and analyze potential failure modes and their consequences, thereby formulating targeted quality control measures and mitigating hospital-acquired infection (HAI) risks.ResultsComparative data before (March to June 2024) and after (October to December 2024) implementation demonstrated significant improvements in key metrics, including instrument cleaning compliance rate, equipment failure frequency, emergency item processing efficiency, and clinical department satisfaction scores. The Risk Priority Numbers (RPN) were markedly reduced (P<0.01) with statistically significant differences.ConclusionA scientific and systematic assessment of HAI risks in CSSD based on the HFMEA and SPO methodologies and in consideration of actual operational conditions effectively mitigates infection risks and enhances medical safety and quality assurance.