Arabic translation and validation of the Subglottic Stenosis Questionnaire-6 items (SGS-6)

Abstract Background The Subglottic Stenosis-6 (SGS-6) is a concise, disease-specific questionnaire designed to assess the severity and progression of subglottic stenosis (SGS), thereby aiding decision-making about the need for intervention. Although it has been validated in English, it has not yet been translated into Arabic. Objectives To translate the SGS-6 into Arabic and validate its psychometric properties in an Arabic-speaking population with SGS. Methods Following forward and backward translation and a comprehension assessment, the Arabic SGS-6 was administered to 28 SGS patients. Internal consistency, test-retest reliability (n = 20), and external validity by correlation with the EuroQoL five-dimension questionnaire (EQ-5D) were analyzed. Results Participants (mean age 44.6 years, 75% female) found the Arabic SGS-6 clear (93%) and easy to complete (96%). Internal consistency was high (Cronbach’s alpha = 0.786 test; 0.812 retest), and test-retest reliability was excellent (ICC = 0.872 single measures; 0.932 average measures). SGS-6 scores correlated significantly with EQ-5D dimensions, notably mobility, usual activities, and pain/discomfort items, confirming external validity. Multiple interventions, the use of inhaled corticosteroids, and dietary modifications were associated with higher SGS-6 scores. The number of previous interventions was the sole independent predictor of SGS-6, suggesting the tool’s sensitivity to disease complexity. Conclusion The Arabic SGS-6 is a reliable, valid, and user-friendly tool for assessing disease severity and QOL in Arabic-speaking SGS patients. Its implementation may improve patient-centered care and guide clinical decision-making, particularly in identifying patients who may require a timely intervention.