Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression
Abstrak
Abstract Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus focusing on the monitoring and treatment of sepsis-induced immunosuppression was developed. Literature related to the immune monitoring and treatment of sepsis were retrieved from PubMed, Web of Science, and Chinese National Knowledge Infrastructure to design items and expert opinions were collected through an online questionnaire. Then, the Delphi method was used to form consensus opinions, and RAND appropriateness method was developed to provide consistency evaluation and recommendation levels for consensus opinions. This consensus achieved satisfactory results through two rounds of questionnaire survey, with 2 statements rated as perfect consistency, 13 as very good consistency, and 9 as good consistency. After summarizing the results, a total of 14 strong recommended opinions, 8 weak recommended opinions and 2 non-recommended opinions were produced. Finally, a face-to-face discussion of the consensus opinions was performed through an online meeting, and all judges unanimously agreed on the content of this consensus. In summary, this expert consensus provides a preliminary guidance for the monitoring and treatment of immunosuppression in patients with sepsis.
Topik & Kata Kunci
Penulis (37)
Fei Pei
Ren-Qi Yao
Chao Ren
Soheyl Bahrami
Timothy R. Billiar
Irshad H. Chaudry
De-Chang Chen
Xu-Lin Chen
Na Cui
Xiang-Ming Fang
Yan Kang
Wei-Qin Li
Wen-Xiong Li
Hua-Ping Liang
Hong-Yuan Lin
Ke-Xuan Liu
Ben Lu
Zhong-Qiu Lu
Marc Maegele
Tian-Qing Peng
You Shang
Lei Su
Bing-Wei Sun
Chang-Song Wang
Jian Wang
Jiang-Huai Wang
Ping Wang
Jian-Feng Xie
Li-Xin Xie
Li-Na Zhang
Basilia Zingarelli
Xiang-Dong Guan
Jian-Feng Wu
Yong-Ming Yao
the Shock and Sepsis Society of Chinese Research Hospital Association
the China Critical Care Immunotherapy Research Group
the International Federation of the Shock Societies (IFSS)
Akses Cepat
- Tahun Terbit
- 2022
- Sumber Database
- DOAJ
- DOI
- 10.1186/s40779-022-00430-y
- Akses
- Open Access ✓