DOAJ Open Access 2021

Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner

Tehasi Wang Chengguang Zhang Shuren Wang

Abstrak

Highlights 1. Circ_0003074 expression was upregulated in OS tissues and cells. 2. Rg3 treatment significantly decreased circ_0003074 expression in OS cells. 3. Circ_0003074 overexpression rescued Rg3-induced inhibition in OS progression. 4. Circ_0003074 induced KPNA4 production through miR-516b-5p under Rg3 treatment.

Topik & Kata Kunci

Orthopedic surgery Diseases of the musculoskeletal system

Penulis (3)

Tehasi Wang

Chengguang Zhang

Shuren Wang

Format Sitasi

APA MLA BibTeX

Wang, T., Zhang, C., Wang, S. (2021). Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner. https://doi.org/10.1186/s13018-021-02868-7

Akses Cepat

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Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.1186/s13018-021-02868-7
Akses: Open Access ✓