Exploring attitudes toward euthanasia in Iranian healthcare providers: a systematic review of influencing factors

Abstract Background Euthanasia is a polarizing topic in healthcare, particularly in Iran, where Islamic principles emphasizing the sanctity of life shape ethical perspectives. Understanding the attitudes of Iranian healthcare providers toward euthanasia and the factors influencing these views is critical, given the cultural and religious context. The primary objective of this study was to systematically identify and synthesize the key factors influencing healthcare providers’ attitudes toward euthanasia in Iran. Methods Following PRISMA guidelines, a systematic search was conducted across PubMed, Scopus, Web of Science, Magiran, and SID databases up to March 10, 2025. Inclusion criteria encompassed observational studies reporting quantitative data on euthanasia attitudes among Iranian healthcare providers. Two reviewers independently screened studies, extracted data, and assessed risk of bias using the Joanna Briggs Institute tools. Due to heterogeneity in study designs and measurement tools, a narrative synthesis was performed. Results Of 595 identified records, 36 studies involving 7,790 participants met inclusion criteria. Attitudes toward euthanasia were predominantly cautious or negative, with stronger opposition among older providers, females, and those with deep religious beliefs. Younger age, male gender, clinical experience, and exposure to terminal patients correlated with more positive attitudes. Religious and cultural factors, particularly Islamic teachings, were significant barriers to acceptance, while urban settings and higher education were linked to neutral or mixed views. Conclusion Iranian healthcare providers’ attitudes toward euthanasia reflect a complex interplay of religious, cultural, and professional influences. These findings underscore the need for enhanced palliative care and ethical training in Iran’s healthcare system to address end-of-life dilemmas while respecting cultural boundaries. Clinical trial number Not applicable.