DOAJ Open Access 2022

Circ-CSNK1G1 promotes cell proliferation, migration, invasion and glycolysis metabolism during triple-negative breast cancer progression by modulating the miR-28-5p/LDHA pathway

Xiaochen Zan Wenfang Li Geng Wang Jie Yuan Yongbiao Ai +2 lainnya

Abstrak

Highlights 1. Circ-CSNK1G1 is upregulated in TNBC. 2. Circ-CSNK1G1 knockdown inhibits the proliferation, migration, invasion and glycolysis energy metabolism of TNBC cells. 3. Circ-CSNK1G1 knockdown inhibits tumor formation in vivo. 4. Circ-CSNK1G1 promotes TNBC development by regulating the miR-28-5p/LDHA pathway.

Topik & Kata Kunci

Gynecology and obstetrics Reproduction

Penulis (7)

Xiaochen Zan

Wenfang Li

Geng Wang

Jie Yuan

Yongbiao Ai

Jun Huang

Zhi Li

Format Sitasi

APA MLA BibTeX

Zan, X., Li, W., Wang, G., Yuan, J., Ai, Y., Huang, J. et al. (2022). Circ-CSNK1G1 promotes cell proliferation, migration, invasion and glycolysis metabolism during triple-negative breast cancer progression by modulating the miR-28-5p/LDHA pathway. https://doi.org/10.1186/s12958-022-00998-z

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Lihat di Sumber doi.org/10.1186/s12958-022-00998-z

Informasi Jurnal

Tahun Terbit: 2022
Sumber Database: DOAJ
DOI: 10.1186/s12958-022-00998-z
Akses: Open Access ✓