DOAJ Open Access 2023

Emerging applications of extracellular vesicles in tumor therapy

Hui Luo Jing Jin Jiajia Jin Kecheng Lou Hailan He +3 lainnya

Abstrak

Abstract Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers. Their physical, chemical and biological characteristics distinguish them as unique carriers with specific pharmacokinetic, circulating metabolic, and biodistribution patterns in the delivery of therapeutic cargoes. They are critical mediators in the pathology of many diseases, including inflammatory diseases, fibrosis, and cancer, but they are also essential mediators in immunomodulation, cancer treatment, infectious defense, and tissue repair. In this review, we emphasize recent advances in oncology therapy using macrophage EVs, mesenchymal stem cell EVs, milk EVs, and plant EVs, as well as the advantages of EVs as delivery platforms and their prospective clinical applications and use.

Topik & Kata Kunci

Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Penulis (8)

Hui Luo

Jing Jin

Jiajia Jin

Kecheng Lou

Hailan He

Shangzhi Feng

Fei Zeng

Junrong Zou

Format Sitasi

APA MLA BibTeX

Luo, H., Jin, J., Jin, J., Lou, K., He, H., Feng, S. et al. (2023). Emerging applications of extracellular vesicles in tumor therapy. https://doi.org/10.1186/s12645-023-00217-3

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Informasi Jurnal

Tahun Terbit: 2023
Sumber Database: DOAJ
DOI: 10.1186/s12645-023-00217-3
Akses: Open Access ✓