DOAJ Open Access 2020

Rapid Diagnosis of Invasive Aspergillosis and Active Hepatitis-B Virus Co-Infection in a HIV-1 Infected Patient Using Cell Free DNA Sequencing

Moni Roy MD, FACP Joseph Y. Kim MD, PhD Rone-Chun Lin MD

Abstrak

Multiple simultaneous opportunistic infections in Human Immunodeficiency virus-1/Acquired immunodeficiency syndrome (HIV-1/AIDS) is a known and dreaded occurrence that often leads to poor outcomes. We present a case of disseminated aspergillosis and active Hepatitis-B virus (HBV) infection in such a host, where cell free DNA (cfDNA) next generation sequencing (NGS) of plasma was used to expedite diagnosis. Bronchoscopy was avoided and treatment was started expeditiously. In this case report we discuss the interpretation of the cfDNA NGS, and its potential role for early diagnosis and avoidance of invasive testing.

Topik & Kata Kunci

Diseases of the genitourinary system. Urology

Penulis (3)

Moni Roy MD, FACP

Joseph Y. Kim MD, PhD

Rone-Chun Lin MD

Format Sitasi

APA MLA BibTeX

FACP, M.R.M., PhD, J.Y.K.M., MD, R.L. (2020). Rapid Diagnosis of Invasive Aspergillosis and Active Hepatitis-B Virus Co-Infection in a HIV-1 Infected Patient Using Cell Free DNA Sequencing. https://doi.org/10.1177/2325958220976263

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Informasi Jurnal

Tahun Terbit: 2020
Sumber Database: DOAJ
DOI: 10.1177/2325958220976263
Akses: Open Access ✓