DOAJ Open Access 2017

Coconut Shell Liquid Smoke Promotes Burn Wound Healing

Vita Murniati Tarawan MD, PhD Kemala Isnainiasih Mantilidewi MD, PhD Ika Miqra Dhini MD, MHS Putri Teesa Radhiyanti MD, MHS Endang Sutedja MD, PhD

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Abstrak

The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups ( P < .05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups ( P < .05). In conclusion, CS-LS promotes burn wound healing by one possible mechanism, by increasing the number of fibroblasts. The results indicate that further experimental trials are needed to develop CS-LS as an alternative topical drug for burn wound healing.

Topik & Kata Kunci

Other systems of medicine Homeopathy

Penulis (5)

Vita Murniati Tarawan MD, PhD

Kemala Isnainiasih Mantilidewi MD, PhD

Ika Miqra Dhini MD, MHS

Putri Teesa Radhiyanti MD, MHS

Endang Sutedja MD, PhD

Format Sitasi

APA MLA BibTeX

PhD, V.M.T.M., PhD, K.I.M.M., MHS, I.M.D.M., MHS, P.T.R.M., PhD, E.S.M. (2017). Coconut Shell Liquid Smoke Promotes Burn Wound Healing. https://doi.org/10.1177/2156587216674313

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Informasi Jurnal

Tahun Terbit: 2017
Sumber Database: DOAJ
DOI: 10.1177/2156587216674313
Akses: Open Access ✓