DOAJ Open Access 2025

Optimization of the Extraction Conditions and Evaluation of Bioactivities of the Phenolic Enrichment From Pandanus amaryllifolius Leaves

Do Hoang Giang Bui Thi Nhat Le Nguyen Thi Thu Minh Nguyen Thi Thu Thuy Nguyen Hai Dang +3 lainnya

Abstrak

This study investigates the optimal conditions to enrich the phenolic content of the extract from Pandanus amaryllifolius leaves and evaluates the bioactivities of this enrichment. The phenolic enrichment was prepared under optimized conditions using the response surface methodology (RSM) with the Box–Behnken design. The antioxidant properties were assessed using DPPH and hydroxyl radical scavenging assays, while the NO production inhibition was measured in LPS-stimulated RAW 264.7 macrophage cells. Results indicated that the phenolic enrichment showed potent antioxidant activity comparable to ascorbic acid and catechin and significantly higher NO inhibition than the separated nonalkaloid and alkaloid fractions. The study also highlights the synergistic effect of phenolic and alkaloid compounds on the antioxidants and anti-inflammatory activities of the phenolic enrichment from Pandanus amaryllifolius leaves.

Topik & Kata Kunci

Analytical chemistry

Penulis (8)

Do Hoang Giang

Bui Thi Nhat Le

Nguyen Thi Thu Minh

Nguyen Thi Thu Thuy

Nguyen Hai Dang

Hoang Le Tuan Anh

Nguyen Ngoc Tung

Nguyen Tien Dat

Format Sitasi

APA MLA BibTeX

Giang, D.H., Le, B.T.N., Minh, N.T.T., Thuy, N.T.T., Dang, N.H., Anh, H.L.T. et al. (2025). Optimization of the Extraction Conditions and Evaluation of Bioactivities of the Phenolic Enrichment From Pandanus amaryllifolius Leaves. https://doi.org/10.1155/jamc/5256388

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.1155/jamc/5256388

Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.1155/jamc/5256388
Akses: Open Access ✓