Use of Rituximab for Dermatomyositis Over Conventional Therapy: A Case Report
Abstrak
We present a case of a woman hospitalized with a known history of systemic lupus erythematosus (SLE) and Type 2 diabetes mellitus. She was referred from a local public district hospital in Richards Bay (KwaZulu-Natal, South Africa) to a tertiary/academic hospital, where her clinical assessment suggested inflammatory myositis. Initially, she presented with a progressively worsening skin rash and proximal muscle weakness. The rash began as red lesions that later healed with pigmentation, primarily in sun-exposed areas. Two weeks after these initial symptoms, she developed scalp hair loss. Her condition eventually deteriorated to the extent that she became bed-bound. A skin biopsy showed dermatomyositis, and a subsequent muscle biopsy confirmed the disease’s typical features. Treatment with rituximab led to improvements in both creatine kinase levels and muscle strength, suggesting its effectiveness in managing her condition.
Topik & Kata Kunci
Penulis (2)
N. N. Ngcobo
L. J. Mathibe
Akses Cepat
- Tahun Terbit
- 2026
- Sumber Database
- DOAJ
- DOI
- 10.1155/crrh/5549943
- Akses
- Open Access ✓