DOAJ Open Access 2025

A Critical Review of the CRISPR-Cas Technology in the Detection of SARS-CoV-2 Variants

Jie Zhang Juezhuo Li Jiawei Zhou Jiaye Zhong Yue Xu +12 lainnya

Abstrak

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still going on, and as the epidemic situation continues, the genome of SARS-CoV-2 is also mutating and evolving, resulting in more and more SARS-CoV-2 mutant strains, which have brought serious pressure on the prevention and control of COVID-19. Given that the COVID-19 is still spreading, it is extremely important to rapidly identify SARS-CoV-2 variants by nucleic acid assays. Thus, developing highly sensitive and specific assays that are suitable for field testing, high-throughput, and automation, as well as other diagnostic applications for SARS-CoV-2 variants, is urgently needed. This paper reviews the research progress of novel CRISPR-based diagnostic methods for SARS-CoV-2 variants.

Topik & Kata Kunci

Infectious and parasitic diseases Microbiology

Penulis (17)

Jie Zhang

Juezhuo Li

Jiawei Zhou

Jiaye Zhong

Yue Xu

Xiaolei Mao

Minghui Xu

Shuyin Luo

Yi Yang

Ruiyao Hu

Dong-Ang Liu

Shiyu Chen

Yuting Qiu

Keyi Chen

Jinghua Yuan

Xinling Zhang

Xiaoping Li

Format Sitasi

APA MLA BibTeX

Zhang, J., Li, J., Zhou, J., Zhong, J., Xu, Y., Mao, X. et al. (2025). A Critical Review of the CRISPR-Cas Technology in the Detection of SARS-CoV-2 Variants. https://doi.org/10.1155/cjid/9107724

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.1155/cjid/9107724
Akses: Open Access ✓