DOAJ Open Access 2024

Triple-Negative Breast Cancer: Tumor Immunogenicity and Beyond

Elio Ibrahim Ernest Diab Rony Hayek Karim Hoyek Hampig Kourie

Abstrak

Triple-negative breast cancer (TNBC) is a breast malignancy with a poor prognosis and limited therapeutic options. Many studies show that TNBC exhibits heterogeneity across clinical, histopathological, and molecular levels. In this review, we discuss the immunogenic features of TNBC with a focus on immunotherapy and the current standard of care in the neoadjuvant, adjuvant, and metastatic setting. In addition, we address the ongoing research on immunotherapy, antibody-drug conjugates (ADCs), poly ADP-ribose polymerase (PARP) inhibitors, and future challenges in the treatment of this entity.

Topik & Kata Kunci

Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Penulis (5)

Elio Ibrahim

Ernest Diab

Rony Hayek

Karim Hoyek

Hampig Kourie

Format Sitasi

APA MLA BibTeX

Ibrahim, E., Diab, E., Hayek, R., Hoyek, K., Kourie, H. (2024). Triple-Negative Breast Cancer: Tumor Immunogenicity and Beyond. https://doi.org/10.1155/2024/2097920

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.1155/2024/2097920

Informasi Jurnal

Tahun Terbit: 2024
Sumber Database: DOAJ
DOI: 10.1155/2024/2097920
Akses: Open Access ✓