DOAJ Open Access 2021

Diarrhea due to SARS-CoV-2-Related Exocrine Pancreatic Insufficiency

Harish K. Patel Jasbir Makker Ahemd Alemam Sridhar Chilimuri

Abstrak

Gastrointestinal symptoms, especially diarrhea, are common with novel coronavirus SARS-CoV-2 infection. Angiotensin-converting enzyme-2 (ACE-2) receptors are heavily expressed in enterocytes and serve as entry receptors for SARS-CoV-2. ACE-2 receptors may also be responsible for pancreatic injury in patients infected with SARS-CoV-2. Diarrhea associated with SARS-CoV-2 is usually believed to be due to viral invasion of enterocytes. However, exocrine pancreatic insufficiency resulting from SARS-CoV-2 is another plausible mechanism leading to diarrhea in such patients. We present a case series of three SARS-CoV-2-infected patients with predominant respiratory symptoms at presentation who developed diarrhea, and further fecal analysis revealed exocrine pancreatic insufficiency as the underlying mechanism.

Topik & Kata Kunci

Diseases of the digestive system. Gastroenterology

Penulis (4)

Harish K. Patel

Jasbir Makker

Ahemd Alemam

Sridhar Chilimuri

Format Sitasi

APA MLA BibTeX

Patel, H.K., Makker, J., Alemam, A., Chilimuri, S. (2021). Diarrhea due to SARS-CoV-2-Related Exocrine Pancreatic Insufficiency. https://doi.org/10.1155/2021/9920981

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Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.1155/2021/9920981
Akses: Open Access ✓