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DOAJ Open Access 2019

Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter

Su Jeong Song Soo-Wang Hyun Tae Gu Lee Bongkyun Park Kyuhyung Jo +2 lainnya
Lihat Sumber DOI

Abstrak

Particulate matter (PM) is a type of air pollutant that poses a risk to human health. In the ocular system, PM causes or aggravates dry eye syndrome (DES) by damaging the corneal and conjunctival epithelia. Liriope platyphylla has been used traditionally as an expectorant, antitussive agent, and tonic in Korea. However, the effects of Liriope platyphylla extract (LPE) on PM-induced ocular damage have not been elucidated. In this study, we evaluated the in vivo protective effect of LPE against PM-induced DES in rats. Topical administration of LPE attenuated the PM-induced decrease in tear volume and reduced corneal epithelial irregularity and damage. LPE also protected against PM-induced disruption of the corneal mucin-4 layer and reduction in the conjunctival goblet cell density. These findings suggest that LPE has protective effects against PM-induced DES.

Topik & Kata Kunci

Ophthalmology

Penulis (7)

S

Su Jeong Song

S

Soo-Wang Hyun

T

Tae Gu Lee

B

Bongkyun Park

K

Kyuhyung Jo

I

Ik Soo Lee

C

Chan-Sik Kim

Format Sitasi

APA MLA BibTeX
Song, S.J., Hyun, S., Lee, T.G., Park, B., Jo, K., Lee, I.S. et al. (2019). Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter. https://doi.org/10.1155/2019/1429548

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Informasi Jurnal
Tahun Terbit
2019
Sumber Database
DOAJ
DOI
10.1155/2019/1429548
Akses
Open Access ✓