DOAJ Open Access 2024

LncRNAs, nuclear architecture and the immune response

Christy Montano Cristina Flores-Arenas Susan Carpenter

Abstrak

Long noncoding RNAs (LncRNAs) are key regulators of gene expression and can mediate their effects in both the nucleus and cytoplasm. Some of the best-characterized lncRNAs are localized within the nucleus, where they modulate the nuclear architecture and influence gene expression. In this review, we discuss the role of lncRNAs in nuclear architecture in the context of their gene regulatory functions in innate immunity. Here, we discuss various approaches to functionally characterize nuclear-localized lncRNAs and the challenges faced in the field.

Topik & Kata Kunci

Genetics Cytology

Penulis (3)

Christy Montano

Cristina Flores-Arenas

Susan Carpenter

Format Sitasi

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Montano, C., Flores-Arenas, C., Carpenter, S. (2024). LncRNAs, nuclear architecture and the immune response. https://doi.org/10.1080/19491034.2024.2350182

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Informasi Jurnal

Tahun Terbit: 2024
Sumber Database: DOAJ
DOI: 10.1080/19491034.2024.2350182
Akses: Open Access ✓