DOAJ Open Access 2018

Bioactivities of peptide fractions derived from proteolytic enzyme-injected Hanwoo longissimus muscle in a model system

Kuk-Hwan Seol Juhui Choe Hyun-Jin Kim Jin-Taek Hwang Mooha Lee +1 lainnya

Abstrak

In this study, crude peptide fractions from Hanwoo loins were released by injecting with proteolytic enzymes [no enzymes (control); protease type XIII (E1); thermolysin (E2); and combination of E1 and E2 (E3)] and their bioactivities were determined. The peptides derived from E2-injected Hanwoo loin exhibited the highest angiotensin I–converting enzyme (ACE) inhibitory activity and vitamin C equivalents antioxidant capacity among the treatments. The released peptide by treatment of E2 and E3 had similar (P > 0.05) inhibitory activity in HT29 cancer cell viability compared with luteolin as a positive control and non-cytotoxic effect on normal cell (3T3-L1). Therefore, the released peptide fraction from thermolysin (E2)-injected Hanwoo beef might contain potent bioactive peptides with ACE inhibitory and antioxidative activity and inhibition effect on certain cancer cell viability.

Penulis (6)

K

Kuk-Hwan Seol

J

Juhui Choe

H

Hyun-Jin Kim

J

Jin-Taek Hwang

M

Mooha Lee

C

Cheorun Jo

Format Sitasi

Seol, K., Choe, J., Kim, H., Hwang, J., Lee, M., Jo, C. (2018). Bioactivities of peptide fractions derived from proteolytic enzyme-injected Hanwoo longissimus muscle in a model system. https://doi.org/10.1080/10942912.2018.1440241

Akses Cepat

Informasi Jurnal
Tahun Terbit
2018
Sumber Database
DOAJ
DOI
10.1080/10942912.2018.1440241
Akses
Open Access ✓