DOAJ Open Access 2022

Non-enzymatic catalytic asymmetric cyanation of acylsilanes

Tagui Nagano Akira Matsumoto Ryotaro Yoshizaki Keisuke Asano Seijiro Matsubara

Abstrak

Catalytic asymmetric cyanation of ketones is a straightforward method to construct tetrasubstituted chiral carbon centers, but for acylsilanes this method has been limited to enzymatic approaches. Here, non-enzymatic catalytic asymmetric cyanation of acylsilanes is accomplished using a chiral Lewis base as an enantioselective catalyst.

Topik & Kata Kunci

Chemistry

Penulis (5)

Tagui Nagano

Akira Matsumoto

Ryotaro Yoshizaki

Keisuke Asano

Seijiro Matsubara

Format Sitasi

APA MLA BibTeX

Nagano, T., Matsumoto, A., Yoshizaki, R., Asano, K., Matsubara, S. (2022). Non-enzymatic catalytic asymmetric cyanation of acylsilanes. https://doi.org/10.1038/s42004-022-00662-y

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Informasi Jurnal

Tahun Terbit: 2022
Sumber Database: DOAJ
DOI: 10.1038/s42004-022-00662-y
Akses: Open Access ✓