DOAJ Open Access 2023

A Strep A vaccine global demand and return on investment forecast to inform industry research and development prioritization

Donald R. Walkinshaw Meghan E. E. Wright Marni Williams Tanya M. F. Scarapicchia Jean-Louis Excler +2 lainnya

Abstrak

Abstract Investment in Strep A vaccine R&D is disproportionately low relative to the large burden of Strep A diseases globally. This study presents a novel Strep A vaccine global demand and financial forecast model with estimates of potential global demand and associated revenue and profits for a hypothetical Strep A vaccine as well as a net present value (NPV) analysis of return on capital investments required to develop the vaccine. A positive NPV was calculated for a variety of developer scenarios and target populations, including the global rollout of the vaccine in private and public markets by a multinational pharmaceutical corporation and a staged rollout by a developing country vaccine manufacturer for both infant and child populations. The results suggest there is a viable commercial market for a Strep A vaccine. It is hoped that this study will help to inform industry decision-making and drive increased prioritization of, and investment in, Strep A vaccine research and development.

Penulis (7)

D

Donald R. Walkinshaw

M

Meghan E. E. Wright

M

Marni Williams

T

Tanya M. F. Scarapicchia

J

Jean-Louis Excler

R

Ryan E. Wiley

A

Anne E. Mullin

Format Sitasi

Walkinshaw, D.R., Wright, M.E.E., Williams, M., Scarapicchia, T.M.F., Excler, J., Wiley, R.E. et al. (2023). A Strep A vaccine global demand and return on investment forecast to inform industry research and development prioritization. https://doi.org/10.1038/s41541-023-00690-2

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Informasi Jurnal
Tahun Terbit
2023
Sumber Database
DOAJ
DOI
10.1038/s41541-023-00690-2
Akses
Open Access ✓