DOAJ Open Access 2023

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Jared S. Elenbaas Upasana Pudupakkam Katrina J. Ashworth Chul Joo Kang Ved Patel +10 lainnya

Abstrak

SVEP1 is linked to numerous human diseases, though its disease-promoting mechanism has remained unclear. Here, the authors identify SVEP1 as a ligand for the orphan receptor PEAR1 and provide insight into the role of this interaction in cardiovascular disease.

Topik & Kata Kunci

Penulis (15)

J

Jared S. Elenbaas

U

Upasana Pudupakkam

K

Katrina J. Ashworth

C

Chul Joo Kang

V

Ved Patel

K

Katherine Santana

I

In-Hyuk Jung

P

Paul C. Lee

K

Kendall H. Burks

J

Junedh M. Amrute

R

Robert P. Mecham

C

Carmen M. Halabi

A

Arturo Alisio

J

Jorge Di Paola

N

Nathan O. Stitziel

Format Sitasi

Elenbaas, J.S., Pudupakkam, U., Ashworth, K.J., Kang, C.J., Patel, V., Santana, K. et al. (2023). SVEP1 is an endogenous ligand for the orphan receptor PEAR1. https://doi.org/10.1038/s41467-023-36486-0

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Informasi Jurnal
Tahun Terbit
2023
Sumber Database
DOAJ
DOI
10.1038/s41467-023-36486-0
Akses
Open Access ✓