DOAJ Open Access 2022

Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase

Ruipeng Lei Timothy J. C. Tan Andrea Hernandez Garcia Yiquan Wang Meghan Diefenbacher +8 lainnya

Abstrak

Lei et al. systematically characterized the epistasis among natural mutations in the neuraminidase of human influenza H3N2 virus, which provide insights into the biophysical constraints that shaped its evolution trajectory over the past half-century.

Topik & Kata Kunci

Penulis (13)

R

Ruipeng Lei

T

Timothy J. C. Tan

A

Andrea Hernandez Garcia

Y

Yiquan Wang

M

Meghan Diefenbacher

C

Chuyun Teo

G

Gopika Gopan

Z

Zahra Tavakoli Dargani

Q

Qi Wen Teo

C

Claire S. Graham

C

Christopher B. Brooke

S

Satish K. Nair

N

Nicholas C. Wu

Format Sitasi

Lei, R., Tan, T.J.C., Garcia, A.H., Wang, Y., Diefenbacher, M., Teo, C. et al. (2022). Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase. https://doi.org/10.1038/s41467-022-34060-8

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Informasi Jurnal
Tahun Terbit
2022
Sumber Database
DOAJ
DOI
10.1038/s41467-022-34060-8
Akses
Open Access ✓