DOAJ Open Access 2021

EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis

Daniel Hidalgo Jacob Bejder Ramona Pop Kyle Gellatly Yung Hwang +9 lainnya

Abstrak

Maturing erythroblasts become smaller with every cell division. Here, the authors show that Epo stimulation promotes cell division and also generates larger red cells, and that this occurs in mouse and human cells, suggesting that red cell size could be a diagnostic marker for hypoxic stress.

Topik & Kata Kunci

Penulis (14)

D

Daniel Hidalgo

J

Jacob Bejder

R

Ramona Pop

K

Kyle Gellatly

Y

Yung Hwang

S

S. Maxwell Scalf

A

Anna E. Eastman

J

Jane-Jane Chen

L

Lihua Julie Zhu

J

Jules A. A. C. Heuberger

S

Shangqin Guo

M

Mark J. Koury

N

Nikolai Baastrup Nordsborg

M

Merav Socolovsky

Format Sitasi

Hidalgo, D., Bejder, J., Pop, R., Gellatly, K., Hwang, Y., Scalf, S.M. et al. (2021). EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis. https://doi.org/10.1038/s41467-021-27562-4

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Informasi Jurnal
Tahun Terbit
2021
Sumber Database
DOAJ
DOI
10.1038/s41467-021-27562-4
Akses
Open Access ✓