DOAJ Open Access 2021

The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes

Matthieu Lacroix Laetitia K. Linares Natalia Rueda-Rincon Katarzyna Bloch Michela Di Michele +18 lainnya

Abstrak

The p53 tumor suppressor is also a regulator of metabolism, but the mechanisms controlling p53-associated metabolic activities remain poorly understood. Here the authors report that the deletion of the multifunctional protein E4F1 is protective against diet-induced obesity in mice, and E4F1 regulates adipocyte lipid metabolism through p53.

Topik & Kata Kunci

Science

Penulis (23)

Matthieu Lacroix

Laetitia K. Linares

Natalia Rueda-Rincon

Katarzyna Bloch

Michela Di Michele

Carlo De Blasio

Caroline Fau

Laurie Gayte

Emilie Blanchet

Aline Mairal

Rita Derua

Fernando Cardona

Diane Beuzelin

Jean-Sebastien Annicotte

Nelly Pirot

Adeline Torro

Francisco J. Tinahones

Florence Bernex

Justine Bertrand-Michel

Dominique Langin

Lluis Fajas

Johannes V. Swinnen

Laurent Le Cam

Format Sitasi

APA MLA BibTeX

Lacroix, M., Linares, L.K., Rueda-Rincon, N., Bloch, K., Michele, M.D., Blasio, C.D. et al. (2021). The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes. https://doi.org/10.1038/s41467-021-27307-3

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.1038/s41467-021-27307-3

Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.1038/s41467-021-27307-3
Akses: Open Access ✓